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Concentrated laxative

Source Antihero's Handbook pg. 28
Price 75 gp; Weight
Type ingested; Save Fortitude DC 12
Onset 10 minutes; Frequency 1/minute for 2 minutes
Effect This mixture gained popularity—and notoriety—when Calistrians used it for elaborate pranks, but now tricksters of all stripes use the colonic concoction for any number of reasons, such as to incommode a nosy interlocutor. After the first failed saving throw, the target is sickened for 1 minute, and after a second failure, the target is nauseated for 1 minute
Cure 1 save